Syngeneic mouse models enable researchers to evaluate immunotherapy candidates in a fully functional immune system. This is done by transferring a mouse tumor cell line into an inbred mouse strain with an intact immune system.
TD2 Syngeneic models are:
- Fully Characterized – Syngeneic tumor models are fully characterized for gene expression, TIL baseline populations, and response to common immune checkpoint inhibitors.
- One Consistent Host — through 16S ribosomal RNA (rRNA) gene sequencing launched before the study even begins, we define the microbiome at the onset, which enables your project focused access to a known and stable host from start to finish.
- Find Effector Cells — through multi-parameter flow cytometry, we can characterize phenotypic immune cell population changes post-treatment.
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