Immunotherapy Models

Syngeneic Mouse Tumor Models

Syngeneic mouse models enable researchers to evaluate immunotherapy candidates in a fully functional immune system. This is done by transferring a mouse tumor cell line into an inbred mouse strain with an intact immune system.

TD2 Syngeneic models are:

• Fully Characterized – Syngeneic tumor models are fully characterized for gene expression, TIL baseline populations, and response to common immune checkpoint inhibitors.
• One Consistent Host — through 16S ribosomal RNA (rRNA) gene sequencing launched before the study even begins, we define the microbiome at the onset, which enables your project focused access to a known and stable host from start to finish.
• Find Effector Cells — through multi-parameter flow cytometry, we can characterize phenotypic immune cell population changes post-treatment.