pk/adme
Seamless program support from oncology experts.
ADME (Absorption, Distribution, Metabolism and Excretion) studies are one of the many services TD2 offers to bring your oncology treatment to market as safely and quickly as possible. Throughout the drug development and approval process, you will have access to a wide variety of ADME assays to support your program along with input from TD2 experts early on.

PK, PD and Biomarkers
Everything needed for successful drug development.
Combining early PK with POC efficacy studies, we provide alignment of compound kinetics from in vitro metabolism through PD and PK testing. TD2 offers Proof of Concept (POC) for both small and large molecules of interest and provides support in the following areas:
- Pharmacokinetic noncompartmental analysis using Phoenix WinNonlin software
- Tissue distribution
- Analysis of large molecules
- Dried Blood Spot (DBS) analysis
- LC-MS/MS and UV-VIS dose confirmation, in support of dose escalation studies