---
title: B16-F10 Syngeneic Model - TD2 Precision Oncology
description: Explore the B16-F10 skin cancer cell line, a valuable model for studying tumor progression and therapeutic interventions in melanoma research.
image: https://td2inc.com/hubfs/Assets/GraphsFigures/b16-f10.png
---
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# B16-F10 Syngeneic Model
**Synonyms:** B16-F10 melanoma cell line, B16-F10 skin tumor cells
B16-F10 is a well-established cancer cell line derived from murine skin melanoma. Widely used in skin cancer research, B16-F10 cells exhibit aggressive tumorigenic behavior and serve as a valuable model for studying tumor progression, metastasis, and therapeutic interventions in melanoma. They have contributed significantly to our understanding of melanoma biology, drug discovery, and immunotherapy. The B16-F10 cell line is particularly relevant for investigating the molecular mechanisms underlying skin cancer and developing novel treatment strategies.
## Model Details
**Cancer Type:** Skin Cancer
**Model Name:** B16-F10
**Mouse Strain:** C57BL/6
**Treatment Data Available:** aPD-1, aPD-L1, aCTLA-4
## B16-F10 Growth Curves: Response to aPD-1, aPD-L1, and aCTLA-4
Growth of subcutaneous B16-F10 in C57BL/6 mice (n=10). Response to aPD-1 dosed Q3Dx6, aPD-L1 dosed Q3Dx6, and aCTLA-4 dosed Q0Dx8.
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