--- title: EMT6 Syngeneic Model - TD2 Precision Oncology description: Discover EMT6, a versatile murine mammary tumor cell line used in breast cancer research. Orthotopic implantation allows the study of tumor progression and treatment response in a clinically relevant environment. image: https://td2inc.com/hubfs/Assets/GraphsFigures/emt6.png --- ×   [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) # EMT6 Syngeneic Model **Synonyms:** EMT-6 mammary carcinoma cell line, EMT6/E5 breast cancer cell line EMT6 is a well-established cancer cell line derived from a murine mammary tumor, widely used in breast cancer research. Apart from investigating tumor biology and therapeutic interventions, EMT6 also offers the advantage of orthotopic implantation. This means the cells can be directly implanted into the mammary fat pad of mice, closely mimicking the natural growth environment of breast tumors. Orthotopic implantation of EMT6 allows researchers to study tumor progression, invasion, metastasis, and response to treatments in a more clinically relevant setting. This model facilitates the evaluation of novel therapeutic strategies and the assessment of treatment efficacy, providing valuable insights into breast cancer development and improving translational research efforts. ## Model Details **Cancer Type:** Breast Cancer **Model Name:** EMT6 **Mouse Strain:** balb/c **Treatment Data Available:** aPD-1 ## EMT6 Growth Curves: Repsonse to aPD-1 ![EMT6 Syngeneic Model](https://td2inc.com/hubfs/Assets/GraphsFigures/emt6.png) Growth of orthotopic EMT6 in balb/c mice (n=10). Response to aPD-1 dosed days 0, 5, 10, 15. ### Request Additional Syngeneic Model Data ## CONTACT US ## Get Started. Have questions about how TD2 can assist with your regulatory needs? Reach out to our expert staff today to get started. [Get Started Now](https://td2inc.com/contact-us/?hsLang=en) [![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/td2-logo.png?width=160&name=td2-logo.png)](https://td2inc.com/?hsLang=en) Office 13208 E. Shea Blvd, Suite 100 Scottsdale, AZ 85259 Phone (602) 358-8300 Connect with us - - ![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/Assets/Logo/acclac-logo.png?width=139&name=acclac-logo.png) © 2026 Translational Drug Development. All Rights Reserved. [Terms and Conditions](https://td2inc.com/terms-and-conditions?hsLang=en) | [Privacy Policy](https://td2inc.com/privacy-policy?hsLang=en)