Immuno-Oncology Therapy: The Power of Syngeneic Tumor Models

Leading the Charge in Immunotherapy Research & Discovery

In the transformative landscape of immuno-oncology, syngeneic mouse models have emerged as invaluable tools, allowing researchers to simulate and assess the dynamics of immunotherapies within an intact, fully functional immune environment. By grafting mouse tumor cell lines into genetically identical mouse strains, we maintain a responsive immune system.

TD2’s specialized syngeneic models stand out with:

1. Comprehensive Characterization – Dive deep into gene expression, TIL baseline populations, and the intricate dance with leading immune checkpoint inhibitors.
2. Consistent Microbial Landscape — With advanced 16S rRNA gene sequencing initiated pre-study, we ensure a consistent microbiome, guaranteeing your research is conducted within a known and unchanging host environment.
3. Effector Cell Profiling — Through the precision of multi-parameter flow cytometry, we decode the changes in immune cell phenotypes post-treatment, setting the stage for more effective and tailored immuno-oncology therapy advancements.