In the sphere of immuno-oncology research, a powerful tool has emerged - the Diet-Induced Obesity (DIO) mouse model. These models provide researchers a practical route to understanding the connections between obesity, immunity, and cancer treatment. The real value of DIO mice lies in their ability to reflect human-like responses, marking a new phase of discovery. Below are the top 5 reasons researchers should be incorporating DIO mice into the preclinical evaluation of immuno-oncology treatments.
August 22, 2023
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In cancer drug development, monotherapies often lose ground when tumors adapt. This is especially true for KRASmutant non–small cell lung cancers ...
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Despite decades of investment in oncology drug development, the translational pipeline from preclinical models to clinical success remains ...
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The FDA has issued a new draft guidance titled “Oncology Therapeutic Radiopharmaceuticals: Dosage Optimization During Clinical Development.” This ...
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