In the sphere of immuno-oncology research, a powerful tool has emerged - the Diet-Induced Obesity (DIO) mouse model. These models provide researchers a practical route to understanding the connections between obesity, immunity, and cancer treatment. The real value of DIO mice lies in their ability to reflect human-like responses, marking a new phase of discovery. Below are the top 5 reasons researchers should be incorporating DIO mice into the preclinical evaluation of immuno-oncology treatments.
August 22, 2023
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Advancing Preclinical Research in Gynecologic Cancers
Gynecologic cancers, including endometrial and ovarian cancers, remain areas of high unmet need. Advances in targeted therapy, immunotherapy, ...
History of CAR T-cells and Their Continued Use in Hematological Malignancies to Advance Next-Generation Therapies
CAR T-cell therapy originated in the late 1980s, first-generation constructs lacked adequate co-stimulatory signaling, causing poor CAR T-cell ...
Cancer Support: Contract Research Organizations, More Than a Vendor, a Partner In Drug Development.
Developing cancer therapies is an incredibly complex, costly, and highly regulated journey. To navigate this challenging terrain, pharmaceutical and ...
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