A673 CDX Model
A673 is a well-characterized human Ewing sarcoma cell line derived from a pediatric patient (female, 15 years old) with a peripheral primitive neuroectodermal tumor (pPNET), which is part of the Ewing sarcoma family of tumors. A673 cells harbor the characteristic EWSR1-FLI1 fusion oncogene, resulting from the t(11;22)(q24;q12) chromosomal translocation that drives Ewing sarcoma pathogenesis.
Cancer Type: Ewing sarcoma
Model Name: A673
Mouse Strain: NSG
Treatment Data Available: Cyclophosamide A673 Growth Curves
Subcutaneous Mean Tumor Growth: A673M Human Ewing Sarcoma in Female NSG mice
Mean Body Weigh Change: A673M Human Ewing Sarcoma in Female NSG mice
