The scientific community has long appreciated the importance of in vivo tumor models for understanding cancer biology and testing therapeutic strategies. Two popular methods for tumor implantation in these models are orthotopic and subcutaneous implantation. Both have their advantages, and the choice often depends on the specific goals of a study. In this post, we'll delve deep into the benefits of each method to guide researchers in their decision-making process.
October 24, 2023
- Model Spotlight: Breast Cancer Clinical Update and Preclinical Plan
- Advancing Preclinical Research in Gynecologic Cancers
- History of CAR T-cells and Their Continued Use in Hematological Malignancies to Advance Next-Generation Therapies
- Cancer Support: Contract Research Organizations, More Than a Vendor, a Partner In Drug Development.
- Advancing Bone and Sarcoma Cancer Research Through Robust In Vivo Models
Model Spotlight: Breast Cancer Clinical Update and Preclinical Plan
Based on the American Cancer Society 2026 estimates and survival statistics, as of October 2026, developments in antibody-drug conjugates (ADCs), ...
Advancing Preclinical Research in Gynecologic Cancers
Gynecologic cancers, including endometrial and ovarian cancers, remain areas of high unmet need. Advances in targeted therapy, immunotherapy, ...
History of CAR T-cells and Their Continued Use in Hematological Malignancies to Advance Next-Generation Therapies
CAR T-cell therapy originated in the late 1980s, first-generation constructs lacked adequate co-stimulatory signaling, causing poor CAR T-cell ...
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