Immunotherapy and cell therapy have revolutionized the field of cancer treatment by harnessing the power of the immune system to fight cancer cells. However, the development of effective immunotherapy drugs such as immune checkpoint inhibitors requires extensive preclinical testing to ensure safety and efficacy. Breakthroughs in the field are faced with several challenges including the generation of appropriate humanized mouse models for preclinical evaluation. Among others, genetically-engineered mouse models have emerged as valuable tools for improving cancer treatment outcomes.
July 13, 2023
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Advancing Bone and Sarcoma Cancer Research Through Robust In Vivo Models
Bone cancers and soft tissue sarcomas represent a diverse group of rare malignancies arising from mesenchymal tissues including bone, muscle, fat, ...
How the FDA’s Plausible Mechanism Framework Signals the Future of Precision Oncology
The FDA’s newly announced Plausible Mechanism Framework marks an important step toward aligning regulatory pathways with the realities of modern ...
What Makes Radioligand Therapy IND Strategy Fundamentally Different?
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