Genetically Engineered Humanized Mouse Models: A Critical Tool for Studying Immunotherapy Drugs

July 13, 2023

Genetically Engineered Humanized Mouse Models: A Critical Tool for Studying Immunotherapy Drugs

Immunotherapy and cell therapy have revolutionized the field of cancer treatment by harnessing the power of the immune system to fight cancer cells. However, the development of effective immunotherapy drugs such as immune checkpoint inhibitors requires extensive preclinical testing to ensure safety and efficacy. Breakthroughs in the field are faced with several challenges including the generation of appropriate humanized mouse models for preclinical evaluation. Among others, genetically-engineered mouse models have emerged as valuable tools for improving cancer treatment outcomes.

A Brief History of Flow Cytometry

By Darcey L. Clark, MS DABT, Senior Biotechnology Professional

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Silent but Deadly, and Beneficial? – Natural Killer Cells

By Jayne Schaubhut, Lab Supervisor Natural Killer (NK) cells play a major role in targeting and killing both tumor cells and virally infected cells ...

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