SW-480 CDX Model
The SW-480 cell line is derived from human colon adenocarcinoma, a common type of colorectal cancer that originates from the epithelial cells of the colon. Colorectal cancer ranks among the leading causes of cancer-related deaths, with its development often tied to genetic mutations, lifestyle factors, and dietary habits. The SW-480 cell line provides a rich resource for exploring the biology, progression, and therapeutic interventions linked to colon adenocarcinoma. Featuring a distinctive molecular signature and genetic mutations emblematic of colon cancer patients, SW-480 holds significant relevance in preclinical studies. Its in vitro and in vivo behavior yields essential insights into tumor growth patterns, metastatic tendencies, and drug response dynamics. Researchers regularly employ the SW-480 model to delve into the molecular intricacies of colon cancer, evaluate the potential of novel therapeutic agents, and discern potential resistance pathways to traditional treatments.
Model Details
Cancer Location: Colon
Cancer Type: Colon Cancer
Model Name: SW-480
Mouse Strain: Nu/Nu
SW480 Growth curves
Growth of subcutaneous SW480 in Nu/Nu mice (n=5 mice).
