MBT-2 Syngeneic Model

Synonyms: MBT2 bladder cancer cell line, MBT-2 bladder tumor cell line

MBT-2 is a well-known cancer cell line derived from murine bladder tumors. It serves as a valuable tool in bladder cancer research, offering insights into tumor biology, metastasis, and therapeutic interventions. The cells exhibit an epithelial morphology and can form tumors when implanted into animal models. Researchers utilize MBT-2 to study various aspects of bladder cancer, including genetic alterations, signaling pathways, immune responses, and drug sensitivity. It has been extensively employed in preclinical models to evaluate the efficacy of different treatment approaches such as chemotherapy, immunotherapy, and targeted therapies. The MBT-2 cell line plays a crucial role in advancing our understanding of bladder cancer and developing new strategies for its diagnosis and treatment.

Model Details

Cancer Type: Bladder Cancer
Model Name: MBT-2
Mouse Strain: C3H
Treatment Data Available: aCTLA-4

MBT-2 Growth Curves

Growth of subcutaneous MBT-2 in C3H mice (n=5)