MB49 Syngeneic Model

Synonyms: MB-49, MB49 murine bladder carcinoma cell line, mouse bladder cancer cell line

MB49 is a well-established cell line derived from murine bladder cancer. It closely resembles human bladder cancer and is used to study tumor growth, metastasis, and treatment response. These epithelial cells form tumors in mice and are valuable for investigating signaling pathways, drug sensitivity, genetic alterations, and immune responses in bladder cancer. MB49 is widely employed in preclinical models to evaluate therapeutic strategies such as chemotherapy, immunotherapy, and targeted therapies. It plays a crucial role in advancing our understanding of bladder cancer and developing novel treatment approaches.

Model Details

Cancer Type: Bladder Cancer
Model Name: MB49
Mouse Strain: C57BL/6
Treatment Data Available: aPD-1

MB49 Growth Curves

Growth of subcutaneous MB49 in C57BL/6 mice (n=10 mice)