Syngeneic mouse models Syngeneic tumor models are fully characterized for gene expression, TIL baseline populations, and response to common immune checkpoint inhibitors.
One Consistent Host — through 16S ribosomal RNA (rRNA) gene sequencing launched before the study even begins, we define the microbiome at the onset, which enables your project focused access to a known and stable host from start to finish.
Find Effector Cells — through multi-parameter flow cytometry, we can characterize phenotypic immune cell population changes post-treatment. See available models
CAR-T capabilities
Having performed more than 100 studies and strong experience with CAR T-cell handling and processing, we have the specialized oncology knowledge to design and execute your adoptive cell therapy program.
TD2 can begin with cryopreserved or fresh CAR T-cells. We use fluorescent-based counting methods rather than manual dye counting to learn more about the viability of the CAR T-cells. Fluorescent counting helps to more accurately determine cell count and viability. See available cell lines
Humanized mice
• Human PBMCs or effector cell engraftment
• Sourced CD34+ humanized mice
