LL/2 Syngeneic Model

Synonyms: LL2, Lewis lung carcinoma 2, Lewis lung cancer cell line

LL/2 is a widely studied cancer cell line commonly used in lung cancer research. Derived from Lewis lung carcinoma in a C57BL/6 mouse, LL/2 cells exhibit aggressive tumorigenic behavior, making them valuable for investigating tumor progression, metastasis, and therapeutic interventions. Their versatility and well-characterized features contribute to advancing our understanding of lung cancer biology and drug discovery.

Model Details

Cancer Type: Lung Cancer
Model Name: LL/2
Mouse Strain: C57BL/6
Treatment Data Available: aPD-1, aCTLA-4, Chemotherapy

LL/2 Growth Curves: Response to aCTLA-4, aPD-1, and Cytoxan

Growth of subcutaneous LL/2 in C57BL/6 mice (n=10). Response to aCTLA-4 dosed Q3D x 4 , aPD-1 dosed Q3D x 4, and Cytoxan dosed QoD x 3 .