---
title: HCT-116-luc Orthotopic Model - TD2 Precision Oncology
description: HCT-116-luc is a luminescent colon cancer cell line used for studying tumor growth and testing therapeutic interventions.
image: https://td2inc.com/hubfs/Assets/GraphsFigures/hct-116-luc.png
---

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# HCT-116-luc Orthotopic Model

**Synonyms:** –

HCT-116-luc is a luminescent colon cancer cell line derived from HCT-116. It expresses luciferase, allowing for non-invasive monitoring of tumor growth and response to therapies using bioluminescence imaging techniques. HCT-116-luc serves as a valuable tool for studying colon cancer, evaluating drug efficacy, and investigating therapeutic approaches. Researchers utilize this cell line to explore colon cancer biology, identify novel targets, and test anti-cancer agents in preclinical studies.

## Model Details

**Cancer Type:** -B-  
**Model Name:** HCT-116-luc  
**Mouse Strain:** CB.17 SCID  
**Treatment Data Available:** N/A

## HCT-116-luc Growth curves

![HCT-116-luc Orthotopic Model](https://td2inc.com/hubfs/Assets/GraphsFigures/hct-116-luc.png)

Growth of HCT-116-luc after IP disseminated injection of CB.17 SCID mice (n=5)

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