GBM75 GBM Model

GBM75, a Patient-Derived Xenograft (PDX) model, is a cornerstone of brain cancer research. Investigate its characteristics to advance our understanding and develop better treatment strategies. PDX models like GBM75 are essential for preclinical drug discovery due to their ability to preserve the genetic and histological features of patient tumors. GBM75 serves as a critical platform for evaluating drug candidates, accelerating the identification of promising treatments, and ultimately improving patient outcomes.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM75
Mouse Strain: Nu/Nu
WES: Yes
RNAseq: Yes
Methylation: Yes
EGFR Exon Varient: EGFRvIII
PDX Treatment: Yes
Patient Treatment History: Yes

GBM75 Survival

Survival of orthotopic intracranial implanted  GBM75 in Nu/Nu mice  (n=5)