GBM59 GBM Model

GBM59, a Patient-Derived Xenograft (PDX) model, is your ally in brain cancer research. Investigate its features to unlock new discoveries and advance the development of effective treatments. PDX models like GBM59 are invaluable for preclinical drug discovery because they faithfully mimic the patient’s tumor environment. GBM59 provides a platform to evaluate the efficacy and safety of drug candidates, streamlining the drug development process and offering promising solutions for brain cancer patients.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM59
Mouse Strain: Nu/Nu
Treatment Data Available: Chemotherapy (Temozolomide), Radiation (2Gy)
WES: Yes
RNAseq: Yes
Methylation: Yes
EGFR Exon Varient: EGFRvIII
PDX Treatment: Yes
Patient Treatment History: Yes

GBM59 Survival

Survival of orthotopic intracranial implanted  GBM59 in Nu/Nu mice  (n=10)

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