GBM43 GBM Model

GBM43 is a Patient-Derived Xenograft (PDX) model designed for brain cancer research. Investigate its unique features to gain insights into the disease’s complexity and develop effective treatments. PDX models like GBM43 are essential tools for preclinical drug discovery, offering a realistic representation of the patient’s tumor environment. GBM43 allows researchers to evaluate potential drug candidates in a controlled setting, enabling the identification of promising treatments and the advancement of personalized medicine for brain cancer patients.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM43
Mouse Strain: Nu/Nu
Treatment Data Available: Chemotherapy (Temozolomide), Radiation (2Gy), CPT-11, Avastin
WES: Yes
RNAseq: Yes
Methylation: Yes
PDX Treatment: Yes
Patient Treatment History: Yes

GBM43 Survival

Survival of orthotopic intracranial implanted  GBM43  in Nu/Nu mice  (n=10)