GBM148 GBM Model

GBM148-derived PDX model serves as a cornerstone for understanding the intricacies of Brain Cancer and treatment responses in preclinical drug discovery. Researchers depend on GBM148 PDX to uncover the complexities of the disease, guiding the development of targeted therapies. This model plays a central role in advancing drug development in Brain Cancer, as it enables researchers to fine-tune treatment strategies and optimize outcomes for patients.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM148
Mouse Strain: Nu/Nu
Treatment Data Available: Chemotherapy (Temozolomide)
WES: Yes
RNAseq: Yes
Methylation: Yes
PDX Treatment: Yes
Patient Treatment History: Yes

GBM148 Survival

Survival of orthotopic intracranial implanted  GBM148 in Nu/Nu mice  (n=5)