GBM12 GBM Model

Use GBM12, a Patient-Derived Xenograft (PDX) model, to delve into the complexities of brain cancer. This model provides a valuable platform for brain cancer research and treatment development. PDX models like GBM12 are essential for preclinical drug discovery because they preserve the genetic and histological features of patient tumors. Researchers can test a variety of treatment strategies on GBM12 to identify the most promising candidates before advancing to clinical trials. By accelerating drug development, GBM12 contributes to improved outcomes for brain cancer patients.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM12
Mouse Strain: Nu/Nu
Treatment Data Available: Chemotherapy (Temozolomide), Radiation
WES: Yes
RNAseq: Yes
Methylation: Yes
PDX Treatment: Yes
Patient Treatment History: Yes

GBM12 Survival

Survival of orthotopic intracranial implanted  GBM12 in Nu/Nu mice  (n=10)