EO771 Syngeneic Model

Synonyms: EO771, EO 771, E0771, EO771 nurine mammary tumor cell line

EO771 is a widely utilized cancer cell line derived from a murine mammary tumor. It is particularly valuable for breast cancer research due to its ability to undergo orthotopic implantation. Orthotopic implantation involves directly injecting E0771 cells into the mammary fat pad of mice, allowing for the study of tumor growth, invasion, metastasis, and therapeutic response in a physiologically relevant setting. This model closely mimics the natural behavior of breast tumors and enables researchers to evaluate novel treatment strategies, assess treatment efficacy, and investigate the underlying mechanisms of breast cancer progression. E0771 is a versatile tool that contributes to advancing our understanding of breast cancer and developing improved therapeutic approaches.

Model Details

Cancer Type: Breast Cancer
Model Name: EO771
Mouse Strain: C57BL/6
Treatment Data Available: aPD-1, aCTLA-4

Eo771 Growth Curves: Response to aPD-1 and aCTLA-4

Growth of orthotopic E0771 in C57BL/6 mice (n=10). Response to aPD-1 dosed Q3Dx4, and aCTLA-4 dosed Q3Dx4