CT-26 Syngeneic Model

Synonyms: CT26, CT26 colon carcinoma cell line

CT-26 is a well-known cancer cell line derived from a murine colon carcinoma. It is widely used as a preclinical model to study various aspects of colorectal cancer. CT-26 cells exhibit characteristics similar to human colon carcinoma, making them valuable for understanding the disease. They possess an epithelial morphology and can form tumors when implanted in animal models. CT-26 is frequently employed to investigate genetic alterations, signaling pathways, immune responses, and drug sensitivity in colorectal cancer research. It serves as a crucial tool in evaluating the efficacy of different treatment approaches, including chemotherapy, immunotherapy, targeted therapies, and combination treatments. The CT-26 cell line plays a significant role in advancing our knowledge of colorectal cancer and developing novel strategies for its diagnosis and treatment.

Model Details

Cancer Type: Colorectal Cancer
Model Name: CT-26
Mouse Strain: balb/c
Treatment Data Available: aPD-1, aPD-L1, aCTLA-4

CT-26 Growth Curves: Response to aPD-1

Growth of subcutaneous CT-26 in balb/c mice (n=10). Response to aPD-1 dosed Q4Dx4.