Colon26 Syngeneic Model

Synonyms: Colon-26 murine colon carcinoma cell line, Colon-26

Colon26 is a widely studied cancer cell line derived from a murine colon carcinoma. It is commonly used as a preclinical model to investigate various aspects of colorectal cancer, including tumor growth, metastasis, and therapeutic interventions. Colon26 cells exhibit characteristics similar to human colorectal cancer, making them valuable for studying the disease. They have an epithelial morphology and can form tumors when implanted in animal models. Researchers utilize Colon26 to explore genetic alterations, signaling pathways, immune responses, and drug sensitivity in colorectal cancer. It has been extensively employed in preclinical models to evaluate the efficacy of different treatment approaches, such as chemotherapy, immunotherapy, targeted therapies, and combination treatments. The Colon26 cell line plays a crucial role in advancing our understanding of colorectal cancer and developing novel strategies for its diagnosis and treatment.

Model Details

Cancer Type: Colorectal Cancer
Model Name: Colon26
Mouse Strain: balb/c
Treatment Data Available: Chemotherapy

Colon26 Growth Curves: Response to 5-FU

Growth of subcutaneous Colon26 in balb/c mice (n=10). Response to 5-FU dosed QDx5.