BT-142 Orthotopic Model

Synonyms: BT142

BT-142 is a cell line derived from human glioblastoma multiforme (GBM), a highly aggressive brain cancer. It serves as a valuable tool for studying GBM pathogenesis and evaluating therapeutic approaches. BT-142 exhibits key molecular features and genetic alterations observed in GBM patients, making it a representative model for preclinical investigations. Its in vitro and in vivo behavior closely mimics the characteristics of GBM, including invasive growth, angiogenesis, and resistance to conventional treatments. Researchers utilize BT-142 to gain insights into GBM biology and to develop novel treatment strategies.

Model Details

Cancer Type: Brain Cancer
Model Name: BT-142
Mouse Strain: Nu/Nu
Treatment Data Available: N/A

BT-142 Survival

Survival of BT-142 after orthotopic intracranial injection in Nu/Nu mice (n=5)