B16-BL6 Syngeneic Model

Synonyms: B16-BL6 melanoma cell line, B16-BL6 skin tumor cells

B16-BL6 is a widely studied cancer cell line derived from murine skin melanoma. It is frequently utilized in skin cancer research due to its aggressive tumorigenic behavior and relevance to melanoma studies. B16-BL6 cells provide a valuable model for investigating tumor progression, metastasis, and therapeutic interventions in melanoma. They have contributed significantly to our understanding of melanoma biology, drug discovery, and immunotherapy. The B16-BL6 cell line serves as an important tool for studying the molecular mechanisms underlying skin cancer and developing innovative treatment strategies.

Model Details

Cancer Type: Skin Cancer
Model Name: B16-BL6
Mouse Strain: C57BL/6
Treatment Data Available: aPD-1, aCTLA-4, Chemotherapy

B16-BL6 Growth Curve: Response to aCTLA-4, aPD-1, and Cyclophosphamide

Growth of subcutaneous B16-BL6 in C57BL/ 6 (n=10). Response to aCTLA-4, aPD-1, and Cyclophosphamide