--- title: A2780 CDX Model - TD2 Precision Oncology description: A2780 is an ovarian cancer cell line extensively used for studying ovarian cancer biology and assessing therapeutic interventions. image: https://td2inc.com/hubfs/Assets/GraphsFigures/a2780.jpg --- ×   [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) # A2780 CDX Model The A2780 cell line is derived from human ovarian cancer, representing a non-mucinous endometrioid phenotype. It is an indispensable tool for studying ovarian cancer pathogenesis and for evaluating therapeutic interventions. A2780 is particularly notable for its sensitivity to cisplatin, making it a benchmark model for assessing chemotherapeutic responses. Furthermore, A2780 exhibits key molecular and genetic features commonly observed in ovarian cancer patients, which provides a representative platform for preclinical investigations. Its in vitro and in vivo behavior accurately portrays the characteristics of ovarian cancer, such as tumor growth, dissemination patterns within the peritoneal cavity, and response to frontline treatments. Researchers employ A2780 to enhance their understanding of ovarian cancer biology and to test and develop innovative treatment strategies, especially those related to chemoresistance mechanisms. ## Model Details **Cancer Location:** Ovary **Cancer Type:** Ovarian Cancer **Model Name:** A2780 **Mouse Strain:** Nu/Nu **Treatment Data Available:** Chemotherapy (Paclitaxel, Cisplatin, Docetaxel) ## A2780 Growth curves ![A2780 CDX Model](https://td2inc.com/hubfs/Assets/GraphsFigures/a2780.jpg) Growth of subcutaneous A2780 in Nu/Nu mice (n=5) ### Request Additional CDX Model Data ## CONTACT US ## Get Started. Have questions about how TD2 can assist with your regulatory needs? Reach out to our expert staff today to get started. [Get Started Now](https://td2inc.com/contact-us/?hsLang=en) [![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/td2-logo.png?width=160&name=td2-logo.png)](https://td2inc.com/?hsLang=en) Office 13208 E. Shea Blvd, Suite 100 Scottsdale, AZ 85259 Phone (602) 358-8300 Connect with us - - ![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/Assets/Logo/acclac-logo.png?width=139&name=acclac-logo.png) © 2026 Translational Drug Development. All Rights Reserved. [Terms and Conditions](https://td2inc.com/terms-and-conditions?hsLang=en) | [Privacy Policy](https://td2inc.com/privacy-policy?hsLang=en)