GBM6 GBM Model

Investigate aggressive brain cancer with GBM6, a Patient-Derived Xenograft (PDX) model that mimics GBM’s features. Use GBM6 to advance brain cancer research and discover innovative treatment options. PDX models like GBM6 offer a unique advantage in preclinical drug discovery by preserving the heterogeneity and genetic profile of the original patient tumors. They allow for personalized testing of drug candidates, helping researchers identify the most effective treatments for individual patients. GBM6 is an indispensable tool for accelerating the development of targeted therapies and improving patient outcomes.

Model Details

Cancer Location: Intracranial
Cancer Type: Brain Cancer
Model Name: GBM6
Mouse Strain: Nu/Nu
Treatment Data Available: Radiation (2Gy), Chemotherapy (Temozolomide)
WES: Yes
RNAseq: Yes
Methylation: Yes
EGFR Exon Varient: EGFRvIII
PDX Treatment: Yes
Patient Treatment History: Yes

GBM6 Survival

Survival of orthotopic intracranial implanted  GBM6  in Nu/Nu mice  (n=5)