B16-F10 Syngeneic Model

Synonyms: B16-F10 melanoma cell line, B16-F10 skin tumor cells

B16-F10 is a well-established cancer cell line derived from murine skin melanoma. Widely used in skin cancer research, B16-F10 cells exhibit aggressive tumorigenic behavior and serve as a valuable model for studying tumor progression, metastasis, and therapeutic interventions in melanoma. They have contributed significantly to our understanding of melanoma biology, drug discovery, and immunotherapy. The B16-F10 cell line is particularly relevant for investigating the molecular mechanisms underlying skin cancer and developing novel treatment strategies.

Model Details

Cancer Type: Skin Cancer
Model Name: B16-F10
Mouse Strain: C57BL/6
Treatment Data Available: aPD-1, aPD-L1, aCTLA-4

B16-F10 Growth Curves: Response to aPD-1, aPD-L1, and aCTLA-4

Growth of subcutaneous B16-F10 in C57BL/6 mice (n=10). Response to aPD-1 dosed Q3Dx6, aPD-L1 dosed Q3Dx6, and aCTLA-4 dosed Q0Dx8.