--- title: NCI-N87 CDX Model - TD2 Precision Oncology description: NCI-N87 stands as a foundational cell line for gastric cancer research, shedding light on the disease's complex biology and guiding the development of therapeutic strategies. image: https://td2inc.com/hubfs/Assets/GraphsFigures/nci-n87.jpg --- ×   [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) # NCI-N87 CDX Model The NCI-N87 cell line originates from human gastric cancer, a malignancy that arises from the lining of the stomach. Gastric cancer is known for its varied histological subtypes and its potential for metastasis, particularly to the peritoneum, liver, and lungs. The NCI-N87 cell line provides a comprehensive platform for exploring the intricate biology, progression, and therapeutic challenges associated with stomach cancer. Representing distinct molecular features and genetic mutations commonly identified in gastric cancer patients, NCI-N87 plays a pivotal role in preclinical studies. The in vitro and in vivo behavior of NCI-N87 offers valuable insights into the growth kinetics, invasive tendencies, and therapeutic responsiveness of gastric tumors. Researchers extensively utilize the NCI-N87 model to study the molecular dynamics of stomach cancer, to assess the impact of novel therapeutic interventions, and to discern potential mechanisms of resistance to established treatments. ## Model Details **Cancer Location:** Stomach **Cancer Type:** Gastric Cancer **Model Name:** NCI-N87 **Mouse Strain:** Athymic Nude **Treatment Data Available:** Chemotherapy (Herceptin, 5-FU) ## NCI-N87 Growth curves ![NCI-N87 CDX Model](https://td2inc.com/hubfs/Assets/GraphsFigures/nci-n87.jpg) Growth of subcutaneous NCI-N87 in Athymic Nude mice (n=5) ### Request Additional CDX Model Data ## CONTACT US ## Get Started. Have questions about how TD2 can assist with your regulatory needs? Reach out to our expert staff today to get started. [Get Started Now](https://td2inc.com/contact-us/?hsLang=en) [![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/td2-logo.png?width=160&name=td2-logo.png)](https://td2inc.com/?hsLang=en) Office 13208 E. Shea Blvd, Suite 100 Scottsdale, AZ 85259 Phone (602) 358-8300 Connect with us - - ![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/Assets/Logo/acclac-logo.png?width=139&name=acclac-logo.png) © 2026 Translational Drug Development. All Rights Reserved. [Terms and Conditions](https://td2inc.com/terms-and-conditions?hsLang=en) | [Privacy Policy](https://td2inc.com/privacy-policy?hsLang=en)