--- title: EO771 Syngeneic Model - TD2 Precision Oncology description: Explore EO771, a versatile murine mammary tumor cell line used in breast cancer research. Orthotopic implantation enables study of tumor behavior and therapeutic responses. image: https://td2inc.com/hubfs/Assets/GraphsFigures/eo771.png --- ×   [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) [![td2-logo](https://td2inc.com/hubfs/td2-logo.png "td2-logo")](https://td2inc.com/?hsLang=en) ![Search Site](https://td2inc.com/hubfs/Assets/Icon/search-icon-1.png) # EO771 Syngeneic Model **Synonyms:** EO771, EO 771, E0771, EO771 nurine mammary tumor cell line EO771 is a widely utilized cancer cell line derived from a murine mammary tumor. It is particularly valuable for breast cancer research due to its ability to undergo orthotopic implantation. Orthotopic implantation involves directly injecting E0771 cells into the mammary fat pad of mice, allowing for the study of tumor growth, invasion, metastasis, and therapeutic response in a physiologically relevant setting. This model closely mimics the natural behavior of breast tumors and enables researchers to evaluate novel treatment strategies, assess treatment efficacy, and investigate the underlying mechanisms of breast cancer progression. E0771 is a versatile tool that contributes to advancing our understanding of breast cancer and developing improved therapeutic approaches. ## Model Details **Cancer Type:** Breast Cancer **Model Name:** EO771 **Mouse Strain:** C57BL/6 **Treatment Data Available:** aPD-1, aCTLA-4 ## Eo771 Growth Curves: Response to aPD-1 and aCTLA-4 ![EO771 Syngeneic Model](https://td2inc.com/hubfs/Assets/GraphsFigures/eo771.png) Growth of orthotopic E0771 in C57BL/6 mice (n=10). Response to aPD-1 dosed Q3Dx4, and aCTLA-4 dosed Q3Dx4 ### Request Additional Syngeneic Model Data ## CONTACT US ## Get Started. Have questions about how TD2 can assist with your regulatory needs? Reach out to our expert staff today to get started. [Get Started Now](https://td2inc.com/contact-us/?hsLang=en) [![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/td2-logo.png?width=160&name=td2-logo.png)](https://td2inc.com/?hsLang=en) Office 13208 E. Shea Blvd, Suite 100 Scottsdale, AZ 85259 Phone (602) 358-8300 Connect with us - - ![td2-logo-footer](https://td2inc.com/hs-fs/hubfs/Assets/Logo/acclac-logo.png?width=139&name=acclac-logo.png) © 2026 Translational Drug Development. All Rights Reserved. [Terms and Conditions](https://td2inc.com/terms-and-conditions?hsLang=en) | [Privacy Policy](https://td2inc.com/privacy-policy?hsLang=en)