---
title: BT-142 Orthotopic Model - TD2 Precision Oncology
description: BT-142 is a glioblastoma multiforme cell line widely used for studying brain cancer and testing therapeutic interventions.
image: https://td2inc.com/hubfs/Assets/GraphsFigures/bt-142.png
---

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# BT-142 Orthotopic Model

**Synonyms:** BT142

BT-142 is a cell line derived from human glioblastoma multiforme (GBM), a highly aggressive brain cancer. It serves as a valuable tool for studying GBM pathogenesis and evaluating therapeutic approaches. BT-142 exhibits key molecular features and genetic alterations observed in GBM patients, making it a representative model for preclinical investigations. Its in vitro and in vivo behavior closely mimics the characteristics of GBM, including invasive growth, angiogenesis, and resistance to conventional treatments. Researchers utilize BT-142 to gain insights into GBM biology and to develop novel treatment strategies.

## Model Details

**Cancer Type:** Brain Cancer  
**Model Name:** BT-142  
**Mouse Strain:** Nu/Nu  
**Treatment Data Available:** N/A

## BT-142 Survival

![BT-142 Orthotopic Model](https://td2inc.com/hubfs/Assets/GraphsFigures/bt-142.png)

Survival of BT-142 after orthotopic intracranial injection in Nu/Nu mice (n=5)

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